8,54 % | EcoR1 Capital, LLC | 5.282.516 | 0 | 31/12/2023 |
5,43 % | T. Rowe Price Associates, Inc. | 3.360.443 | 295.961 | 31/12/2023 |
5,38 % | State Street Global Advisors (US) | 3.326.856 | 348.255 | 31/12/2023 |
4,14 % | Fidelity Management & Research Company LLC | 2.562.691 | -528.990 | 31/12/2023 |
2,43 % | Armistice Capital LLC | 1.500.000 | 22.000 | 31/12/2023 |
2,19 % | T. Rowe Price Investment Management, Inc. | 1.351.367 | -2.426.996 | 31/12/2023 |
2,13 % | Geode Capital Management, L.L.C. | 1.314.943 | 54.991 | 31/12/2023 |
2,07 % | Dimensional Fund Advisors, L.P. | 1.279.077 | -172.270 | 31/12/2023 |
16,29 % | BlackRock Institutional Trust Company, N.A. | 10.073.333 | 637.886 | 31/12/2023 |
14,40 % | PRIMECAP Management Company | 8.901.607 | 717.401 | 31/12/2023 |
10,93 % | The Vanguard Group, Inc. | 6.755.536 | 115.886 | 31/12/2023 |
1,60 % | Loomis, Sayles & Company, L.P. | 988.244 | -518.308 | 31/12/2023 |
1,21 % | Johnson & Johnson Innovation-JJDC, Inc. | 748.062 | 0 | 31/12/2023 |
1,19 % | BlackRock Financial Management, Inc. | 736.235 | 191.124 | 31/12/2023 |
1,16 % | Two Sigma Investments, LP | 714.927 | 255.151 | 31/12/2023 |
1,15 % | Candriam Belgium S.A. | 707.984 | 55.000 | 31/12/2023 |
1,15 % | Candriam Luxembourg S.A. | 707.965 | 0 | 29/2/2024 |
0,95 % | Northern Trust Investments, Inc. | 585.429 | 47.872 | 31/12/2023 |
0,84 % | Charles Schwab Investment Management, Inc. | 520.698 | 32.251 | 31/12/2023 |
0,73 % | Morgan Stanley & Co. LLC | 453.846 | 60.518 | 31/12/2023 |
0,68 % | JP Morgan Asset Management | 420.670 | -45.579 | 31/12/2023 |
0,57 % | Millennium Management LLC | 350.214 | -377.254 | 31/12/2023 |
0,56 % | Goldman Sachs & Company, Inc. | 348.529 | 232.128 | 31/12/2023 |
0,55 % | Principal Global Investors (Equity) | 342.010 | -4.107 | 31/12/2023 |
0,53 % | Norges Bank Investment Management (NBIM) | 325.439 | -213.506 | 31/12/2023 |
0,49 % | Mellon Investments Corporation | 300.376 | -2.407 | 31/12/2023 |
0,47 % | Parametric Portfolio Associates LLC | 289.030 | 133.602 | 31/12/2023 |
0,45 % | ExodusPoint Capital Management, LP | 280.813 | -14.125 | 31/12/2023 |
0,44 % | Dahiyat (Bassil Ishmael) | 270.508 | 39.269 | 11/3/2024 |
0,40 % | Baker Bros. Advisors LP | 245.431 | 122.304 | 31/12/2023 |
0,40 % | Hudson Bay Capital Management LP | 245.000 | 12.500 | 31/12/2023 |
0,38 % | DCF Advisers, LLC | 237.107 | -9.193 | 31/12/2023 |
0,37 % | Columbia Threadneedle Investments (US) | 226.602 | -67.191 | 31/12/2023 |
0,36 % | Rhenman & Partners Asset Management AB | 225.000 | 0 | 31/12/2023 |
0,35 % | PanAgora Asset Management Inc. | 218.288 | 65.568 | 31/12/2023 |
0,31 % | BlackRock Investment Management, LLC | 189.471 | -571 | 31/12/2023 |
0,30 % | Rhumbline Advisers Ltd. Partnership | 184.831 | 4.862 | 31/12/2023 |
0,30 % | Invesco Capital Management LLC | 183.194 | -328.953 | 31/12/2023 |
0,29 % | Renaissance Technologies LLC | 180.300 | 136.000 | 31/12/2023 |
0,29 % | BlackRock Advisors (UK) Limited | 177.066 | 8.982 | 31/3/2024 |
0,28 % | abrdn Inc. | 175.520 | 175.520 | 31/12/2023 |
0,28 % | UBS Asset Management (Americas), Inc. | 171.972 | -2.394 | 31/12/2023 |
0,27 % | Legal & General Investment Management Ltd. | 170.021 | 2.357 | 31/12/2023 |
0,27 % | Citadel Advisors LLC | 169.476 | 141.151 | 31/12/2023 |
0,27 % | Barclays Bank PLC | 168.499 | 63.582 | 31/12/2023 |
0,27 % | Schonfeld Strategic Advisors LLC | 166.111 | 166.111 | 31/12/2023 |
0,27 % | BNY Mellon Asset Management | 165.049 | 6.600 | 31/12/2023 |
0,27 % | Nuveen LLC | 164.881 | 14.789 | 31/12/2023 |
0,25 % | Russell Investments Trust Company | 156.618 | 23.892 | 31/12/2023 |
0,25 % | Segall Bryant & Hamill, LLC | 154.824 | 504 | 31/12/2023 |
0,25 % | BlackRock Asset Management Ireland Limited | 152.613 | 9.465 | 31/12/2023 |
0,24 % | Qube Research & Technologies Ltd | 145.846 | 110.360 | 31/12/2023 |
0,22 % | Silvercrest Asset Management Group LLC | 137.941 | 0 | 31/12/2023 |
0,22 % | Cubist Systematic Strategies, LLC | 137.089 | 113.533 | 31/12/2023 |
0,22 % | Desjarlais (John R) | 135.201 | 12.815 | 11/3/2024 |
0,22 % | New Jersey Division of Investment | 133.752 | 23.399 | 31/12/2023 |
0,21 % | Macquarie Investment Management | 129.191 | 0 | 31/12/2023 |
0,20 % | PSP Investments | 126.331 | 51.414 | 31/12/2023 |
0,20 % | Putnam Investment Management, L.L.C. | 125.833 | -3.000 | 31/12/2023 |
0,20 % | T. Rowe Price International Ltd | 123.332 | 2.880 | 31/12/2023 |
0,20 % | TD Asset Management Inc. | 123.250 | -56.914 | 31/12/2023 |
0,19 % | Rafferty Asset Management LLC | 119.818 | 9.131 | 31/12/2023 |
0,19 % | BofA Global Research (US) | 119.372 | 30.360 | 31/12/2023 |
0,17 % | Schweizerische Nationalbank | 107.500 | -12.000 | 31/12/2023 |
0,16 % | Dimensional Fund Advisors, Ltd. | 100.374 | 1.436 | 31/1/2024 |
0,16 % | Barclays Capital Inc. | 100.000 | 100.000 | 31/12/2023 |
0,16 % | Northern Trust Global Investments | 99.456 | -921 | 31/12/2023 |
0,16 % | Mutual of America Capital Management LLC | 99.335 | 42.364 | 31/12/2023 |
0,16 % | Credit Suisse Funds AG | 96.110 | 10.957 | 31/12/2023 |
0,15 % | Trexquant Investment LP | 93.759 | 58.672 | 31/12/2023 |
0,15 % | Engineers Gate Manager, L.P. | 89.805 | 78.923 | 31/12/2023 |
0,14 % | Goldman Sachs Asset Management, L.P. | 89.371 | 22.409 | 31/12/2023 |
0,14 % | Kuch John J | 87.719 | -5.323 | 11/3/2024 |
0,14 % | Jump Financial, LLC | 84.689 | 61.574 | 31/12/2023 |
0,14 % | Manulife Investment Management (North America) Limited | 83.591 | -553 | 31/12/2023 |
0,13 % | BNP Paribas Securities Corp. North America | 82.488 | 42.403 | 31/12/2023 |
0,13 % | Citi Investment Research (US) | 82.157 | 11.868 | 31/12/2023 |
0,13 % | BlackRock Investment Management (UK) Ltd. | 81.665 | 15.721 | 31/12/2023 |
0,13 % | AllianceBernstein L.P. | 77.700 | 0 | 31/12/2023 |
0,12 % | GWL Investment Management Ltd. | 75.215 | -2.037 | 31/12/2023 |
0,11 % | Avantis Investors | 70.271 | 21.002 | 31/3/2024 |
0,11 % | PGIM Quantitative Solutions LLC | 69.955 | -638 | 31/12/2023 |
0,11 % | JPMorgan Private Bank (United States) | 68.264 | 41.196 | 31/12/2023 |
0,11 % | UBS Asset Management (Switzerland) | 65.492 | -317 | 31/12/2023 |
0,10 % | American Century Investment Management, Inc. | 62.290 | 16.772 | 31/12/2023 |
0,10 % | Valente (Nancy M.D.) | 58.930 | 19.634 | 5/3/2024 |
0,09 % | New York State Teachers' Retirement System | 58.526 | -300 | 31/12/2023 |
0,09 % | California State Teachers Retirement System | 58.086 | -2.758 | 31/12/2023 |
0,09 % | Tekla Capital Management LLC_NLE | 56.675 | 56.675 | 30/6/2023 |
0,09 % | Aperio Group, LLC | 56.519 | 19.359 | 31/12/2023 |
0,09 % | NFJ Investment Group, LLC | 55.538 | 991 | 31/12/2023 |
0,09 % | Thrivent Asset Management, LLC | 54.244 | -1.205 | 31/12/2023 |
0,09 % | Texas Permanent School Fund | 52.587 | 1.109 | 31/12/2023 |
0,08 % | Polen Capital Management, LLC | 52.117 | -9.142 | 29/2/2024 |
0,08 % | Irish Life Investment Managers Ltd. | 48.972 | -2.003 | 30/9/2023 |
0,08 % | Brown Advisory | 48.365 | -752 | 29/2/2024 |
0,08 % | Aigen Investment Management, LP | 47.666 | 37.128 | 31/12/2023 |
0,08 % | State of Wisconsin Investment Board | 46.887 | -349 | 31/12/2023 |
0,07 % | Capula Investment Management LLP | 45.849 | 3.029 | 31/12/2023 |
0,07 % | Invesco Advisers, Inc. | 44.252 | 595 | 31/12/2023 |